FERTILITY CLINIC MANCHESTER
When undergoing treatment for fertility in Manchester, the last thing you need is to worry about is the cost. That’s why we’ve created a range of prepay plans to give you peace of mind.
Our dedicated team, based in Manchester, includes some of the leading surgeons and specialists in the UK. Together, we provide innovative procedures, fertility treatments & IVF, giving you the best possible chance of a successful outcome.
We offer complete fertility profiling in Manchester, including hormonal screens, ovarian reserve tests, sperm quality tests, and more. If you would like reassurance about your current fertility profile, find out more and contact us today.
If you are experiencing difficulties with conceiving, fertility screening in Manchester can highlight any problems that may be affecting your chances of a successful outcome. Fertility screening encompasses a selection of specialised tests, including full investigations of both partners.
For many years, we have provided ICSI & IVF in Manchester to couple seeking alternative fertility treatments in order to conceive. With a high success rate, you can rest assured that you are in safe, professional hands if you choose specialist treatments, ICSI & IVF, from Aurora.
If you considering becoming an egg donor, here at Aurora Healthcare, we provide a professional service for egg sharing & egg donation in Manchester. The demand for egg donors continues to rise, and we are pleased to be able to facilitate this service for our patients.
If you are, or believe you are, suffering from endometriosis in Manchester, we are here for you. At Aurora Healthcare, our team are specially skilled and expertly trained to provide a wide range of medical and surgical treatments for endometriosis and pelvic pain.
Recurrent miscarriages can be very traumatic. In a lot of cases, repeat miscarriages are caused by underlying issues which can be treated to improve the outcome of future pregnancy. If you are experiencing recurrent miscarriages in Manchester, we are here for you.
What is IVF?
Here, the eggs are fertilised outside of the body and the resulting embryo is transferred into the womb. Following the pioneering work of Gynaecologist Patrick Steptoe and Scientist Robert Edwards in the 1970s, the technique has been refined over the years. Over sixty thousand babies have been born in the UK from IVF and currently about 2% of babies born every year in the UK are ‘IVF babies’. IVF in Manchester is perhaps one of our most commonly used methods of assisted conception.
Who is IVF for?
IVF was originally introduced to help women with blocked or damaged fallopian tubes achieve live births, but it now represents the ultimate treatment for any form of infertility that fails to respond to other conventional treatment. UK law currently allows any woman below the age of 55 years to have this treatment. We are comfortable treating women using their own eggs below the age of 45 and 51 years of age using donated eggs. At Aurora Healthcare, we are pleased to be able to offer IVF in Manchester and the surrounding areas to our patients who require assisted conception.
IVF in Manchester – FAQs
HOW IS IVF REGULATED?
The Human Fertilisation and Embryology Authority (HFEA) was established in 1991 to license clinics that offer IVF, monitor the treatment, and regulate research that involves human eggs, sperm and embryos. It publishes an annual guide of clinics. As a leading fertility clinic, the IVF in Manchester that we offer to our patients is regulated by the HFEA.
HOW IS IVF PERFORMED?
It is important to understand that IVF is a complex process of up to 7 weeks from start to finish. It may take longer to know whether it is successful. The more prepared you are going in, the better you can cope with the demands of the treatment. During your initial consultation for IVF in Manchester, our expert team of fertility specialists would be more than happy to answer any questions you may have.
TREATMENT STEPS FOR IVF
An initial assessment includes a full interview and examination of the female and/or male partner. Blood tests like Follicle Stimulating Hormone (FSH), Luteinising Hormone (LH), Oestradiol, Anti-Mullerian Hormone and blood count are performed to establish the woman’s hormone profile. Couples undergo a virology screen for HIV, hepatitis B, hepatitis C and syphilis. The male partner’s sperm sample is assessed for count, movement, proportion of normal forms of sperm and presence of antibodies. Urine is obtained from both partners to exclude genital tract infections.
Counselling is not mandatory, but can be of immense help in preparing yourself with some of the difficulties you may encounter. We would encourage you to take advantage of our on-site counselling services.
The mainstay of IVF is controlled stimulation of the ovaries to generate growth of many eggs. Two different types of injections are used, which are typically started at the early and late stages in the menstrual cycle. Pelvic ultrasound scans and blood tests are used to monitor the response to stimulation. This continues until the eggs are mature enough to be collected.
Mature eggs are collected from the ovaries in theatre usually under sedation but sometimes under full general anaesthesia. Usually, this is done by gently guiding a needle into the ovaries through the vagina under ultrasound control. On occasion, the eggs are collected by laparoscopy (keyhole surgery). Women typically spend half the day in hospital and are able to return home about lunchtime that day. We usually commence a five-day course of antibiotics from the egg collection.
MIXING EGGS WITH SPERM
The male partner produces a semen sample on the day of egg collection after two to four day abstinence from ejaculation, to ensure good-quality sperm. Tests determine the highest quality semen, which is inseminated into the eggs, which is left overnight in an incubator. The inseminated eggs are checked the next morning to see how many have been fertilised.
The embryos are cultured in a special lab incubator and one or two of the best quality embryos are transferred into the womb two to five days later. The procedure does not usually require any anaesthetic or sedation. We discuss and agree the number of embryos to be transferred beforehand but generally encourage most women to have single embryo transfer. Any good quality embryos that have not been utilised can be frozen for the couple’s future use.
We advise women to continue with their normal schedule following embryo transfer. Hormone pessaries are given afterwards to help the developing embryos. If treatment is unsuccessful, a period will begin one to two weeks after the transfer. Women who have not had a period by this time are offered a pregnancy test and if positive, a pelvic examination follows.
WHAT CAN GO WRONG WITH IVF
Three out of four women will complete the treatment without any difficulties or problems. Common problems encountered include:
Poor response to stimulation – although the ovarian reserve test gives us an indication of how you will likely react to treatment, we sometimes encounter poor stimulation response. There is the option to use a higher dose of stimulation drugs in a subsequent cycle.
Excessive response to stimulation – this can result in a condition called ‘ovarian hyperstimulation syndrome’ that affects one in ten women. It can cause abdominal pain and bloating, vomiting, shortness of breath and fatigue. Severe cases may require hospitalisation or even become life-threatening, but this is fortunately very rare.
Injuries during egg recovery – the needle used for the egg recovery may cause injury to the organs in the pelvis (such as the bladder, intestines, and blood vessels) but this is rare.
Pelvic infections – there is a small risk of infection following the egg collection and severe cases may result in pelvic pus collection. We prescribe antibiotics after egg collection as a preventative measure.
Multiple pregnancies – there is a risk of multiple pregnancies, particularly with replacement of more than one embryo, which is why we encourage women to have single embryo replacement.
Abnormalities in babies – babies born following IVF treatment have slightly greater risks of structural and genetic/chromosomal abnormalities.
EGG DONATION AND SHARING FOR IVF
Donated Sperm, Eggs and Embryos
IVF can be undertaken with donated sperm and eggs, also called gametes. The HFEA has strict regulations governing treatment with donated gametes and these will be discussed with any couple to whom they apply. Some women cannot produce their own eggs due to premature menopause, so need donated eggs or embryos. Women with abnormal eggs and those with a genetic abnormality can also use donated eggs or embryos. Men who cannot produce their own sperm can utilise donated sperm.
Any healthy man, woman or couple that is free of genetic or transmittable diseases can potentially donate their gametes after undergoing a screening process. Factors considered include detailed examination, blood tests for chromosomes and infections like HIV, hepatitis B, hepatitis C, syphilis and cytomegalovirus, and cervical swabs.
Egg sharing is a special form of egg donation, whereby two women undergo IVF treatment simultaneously. The recipient effectively pays for the treatment, and eggs are retrieved from another donor which have a better chance of becoming embryos. All previously described processes remain the same.
Ethical Issues with Gamete Donation
There are implications of using donated gametes that all involved parties need to be aware of:
Payment of donors – this is a contentious issue and the legislation concerning it varies from country to country. The current UK legislation holds that sperm, egg and embryo donation should be performed altruistically and not attract any form of payment, except where this is to cover loss of income or reasonable expenses incurred by the donor in the process of the donation.
Egg sharing – couples contemplating egg sharing should agree on all aspects of the treatment thoroughly beforehand and agree a plan of how the eggs are shared and how any future problems are dealt with. These include success in one but not the other couple.
Anonymity – legislation in the UK has recently changed to give offspring of sperm, egg and embryo donation cycles the right to find out the identity of their genetic parents once they reach their eighteenth birthday.
Legal parents – current legislation in the UK holds that a married man and woman receiving treatment are the legal parents of any child that results. For unmarried couples, both partners are not automatically awarded legal parent status and have to apply for this at the time of consenting to treatment or through the courts.
Informing the child – most clinics recognise that children have the right to know about their conception and some arrange a yearly reunion for children born from this and other forms of assisted conception methods to reinforce the normality of such children. Counselling is available at all licensed clinics to discuss the implications of using donated gametes.
IVF & FROZEN EMBRYO REPLACEMENT
Couples with frozen embryos can have these transferred without the need to undergo another stimulation cycle. Frozen embryos have a 60-90% chance of surviving freezing. The embryos can be transferred in natural or hormone-prepared cycles. Natural cycles are suitable for women with regular ovulation while those with irregular periods need preparation of the womb using hormone tablets, pessaries (vaginal tablets) and injections. The artificial hormones used to prepare the womb will need to be continued for some time after the transfer; generally up to 12 weeks if pregnancy ensues. Details of transfer procedures, number of embryos transferred and what happens afterwards will be discussed fully with couples.
IVF TREATMENT SUCCESS RATES
In vitro fertilisation has made it possible for many couples to fulfil their dreams of having children, although treatment is not always successful. Factors that improve the chances of success include: young female age (particularly under thirty), previous pregnancies, and short duration of infertility. Success is measured professionally by pregnancy and life-birth rates and current average rates in the UK are detailed in the table below.
|Age Groups||Fresh IVF/ICSI cycles||Frozen embryo cycles||IVF with Donated Eggs||IVF with Donated Sperm||DI cycles without drugs||DI cycles with drugs|
|< 35 years||32.8%||28.3%||30.7%||31.2%||21.6%||13.4%|
|> 44 years||2.0%||–||29.3%||–||–||–|
Table 1. Live birth rates for assisted conception cycles in the UK; HFEA published results 2014.
Personal Assistant and Client Liaison Manager
Dr Edi-Osagie and his team are amazing and were so caring and understanding of our circumstances. I was very nervous in a hospital environment, but Dr Edi-Osagie put me at ease and explained everything so open and honestly, allowing us to make the choices that were right for us. In doing so, we now cradle in our arms our beautiful daughter.
The treatment we received was completely tailored to our needs and each step of the process was fully explained. Edi and his team have fulfilled our dreams of becoming parents and for this we cannot thank them enough.
We cannot even begin to thank Dr. Osagie and his team for the care and support we have received over the last few years. Edi and his staff are not only professional but kind, compassionate and personable.
Under the care of Dr Edi Osagie and Dr Sajjad we managed to achieve a successful pregnancy after many years of trying and a lot of heartache along the way. We found Aurora to be at the cutting edge of all new developments in fertility treatment. The staff at Aurora treated us with compassion and understanding along our journey and were available 24/7 should we have needed them. We would have no hesitation in recommending Aurora to anyone.
Aurora have given us the family we thought we would never have and we can’t thank them enough. IVF is such a huge investment, both emotionally and financially and it is so important that you find the right clinic. Dr Edi-Osagie was so professional throughout, explaining the process in clear and simple terms and the nurses were kind, knowledgeable and showed a great deal of empathy when it was needed. We can’t recommend Aurora highly enough to anyone struggling with infertility.